Manual de Exames


Letra I


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IGFBP-3 - Proteína ligadora IGF-I tipo 3

Material:

Soro

Instruções de coleta:

Coletar em tubo sem anticoagulante, separar o soro e congelar

Informações:

Avaliação de várias situações clínicas (atraso no crescimento, acromegalia, estado nutricional). A secreção de GH (hormônio do crescimento) flutua ao longo do dia, tendo uma meia vida de 15 a 20 minutos. As concentrações de IGFBP-3 têm uma variação diária muito pequena, podendo oferecer informação mais segura e útil. Os níveis de IGFBP-3 são menos dependentes da idade, sendo mais altos em crianças jovens que os níveis de IGF-1. Isto permite uma melhor diferenciação entre os níveis normais e subnormais. As dosagens de IGFBP-3 são úteis também para monitorar a eficácia do tratamento por deficiência de GH. Uma combinação das dosagens de IGFBP-3 e IGF-1 pode prover uma melhor avaliação quanto à avaliação de estatura baixa em crianças. Valores aumentados: acromegalia. Valores diminuídos: atraso no crescimento, estado nutricional.

Referência:

  • Idade(anos): Homem(ng/mL) : Mulher(ng/mL)
  • 0 a 1 : 1030,0 a 3090,0 : 1030,0 a 3090,0
  • 2 a 7 : 1100,0 a 4230,0 : 1100,0 a 4230,0
  • 8 a 11 : 1250,0 a 7060,0 : 2060,0 a 7740,0
  • 12 a 18 : 1820,0 a 7060,0 : 1800,0 a 7740,0
  • 19 a 30 : 1730,0 a 7380,0 : 2050,0 a 7600,0
  • 31 a 40 : 1730,0 a 7260,0 : 1730,0 a 7260,0
  • 41 a 70 : 2020,0 a 4310,0 : 2020,0 a 4310,0
  • 71 ou mais: 2698,0 a 5688,0 : 2462,0 a 5274,0
 

Laboratório Bioclinico

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